Core Concepts of Neural Anatomy and Signaling

Nervous System Structure and Function

The Nervous System (NS) maintains body temperature, monitors, integrates, and responds to information in the environment.

Divisions of the Nervous System

  • Central Nervous System (CNS): Includes the brain and spinal cord.
  • Peripheral Nervous System (PNS): Includes cranial and spinal nerves.

PNS Divisions

  1. Sensory (Afferent) Division: Conveys impulses to the CNS.
  2. Motor (Efferent) Division: Conveys impulses from the CNS.
    • Somatic (Voluntary) System: Serves skeletal muscles.
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Endocrine System: Functions of Key Glands and Hormones

Hypothalamus: Central Regulator of Body Functions

Regulation of Hunger and Satiety

The hypothalamus regulates hunger, appetite, and satiety through various hormones and peptides, such as cholecystokinin, glucose and fatty acids in the blood, and neuropeptide Y, among others.

  • The hunger center is located in the lateral hypothalamus.
  • The satiety center is located in the ventromedial portion.

Temperature Control

The hypothalamus plays a crucial role in thermoregulation:

  • The anterior hypothalamus is involved
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Essential Physiology: GI, Renal, Endocrine, and Sensory Systems

The Digestive System: Structure and Function

Functions of the digestive system include: ingestion, secretion, mixing, propulsion, digestion, absorption, and defecation.

Layers of the GI Tract Wall

  • The mucosa is the innermost layer of the GI tract.
  • The Serosa is the outermost layer.
  • The Serosa is called the visceral peritoneum in portions of the GI tract suspended in the abdominopelvic cavity.
  • The Serosa is called the Adventitia in the esophagus.

Innervation and Secretions

  • The lower portion of the large
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Cardiac Reentry Arrhythmias and Antiarrhythmic Drug Mechanisms

Mechanisms of Reentry Arrhythmias

The following scenarios illustrate the development of reentrant arrhythmias:

  • B: Interruption of Stimulus (Prolonged Refractory Period)

    This represents the momentary interruption of the stimulus due to tissue damage that prolongs the refractory period. This tissue is not dead but exhibits a lengthening of the refractory period, perhaps due to localized hypoxia (lack of oxygen). The impulse in the right branch is interrupted, but the impulse in the left branch continues

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Kidney Anatomy and Urine Production Process

Kidney Anatomy and Structure

Kidneys are paired, bean-shaped organs located on the back of the abdomen, above the waist, and on both sides of the spine. Renal arteries supply blood to the kidneys, renal veins carry blood away, and ureters transport urine to the urinary bladder. From the outside, the kidney shows the following areas:

  • Renal Capsule: A fibrous, clear membrane that surrounds and protects the kidney.
  • Renal Cortex: The outer, dark red zone, composed of connective tissue.
  • Renal Medulla: Lighter
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Nephron: Kidney Structure, Function, and Regulation

The nephron is the functional unit of the kidney. Each kidney contains approximately 1 million nephrons, which do not regenerate if destroyed. From age 40, approximately 1% of nephrons are lost each year.

Components of the Nephron

The nephron is primarily formed by the glomerulus and the tubular system.

Glomerulus

An afferent arteriole, originating from the renal artery, reaches the glomerulus and branches into glomerular capillaries. These capillaries are highly permeable—approximately 400 times

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