Animal

Applications of cell culture

Cell culture is one of the major tools used in cellular and molecular biology, providing excellent

model systems for studying the normal physiology and biochemistry of cells (e.G., metabolic

studies, aging), the effects of drugs and toxic compounds on the cells and mutagenesis and

carcinogenesis. It is also used in drug screening and development and large scale manufacturing

of biological compounds (e.G., vaccines, therapeutic proteins). The major advantage of using cell

culture

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Molecular Biology Techniques: Gene Therapy and cDNA Library Creation

Gene Therapy: Concepts and Applications

Ever since the dawn of mankind, diseases have plagued humans over the ages. Years of innovations and advancements in science have provided us with a deeper understanding of how diseases work. This has led to lower mortality rates and longer lifespans. But there are some diseases that just cannot be cured using traditional medicine or surgery. Gene therapy is an experimental technique that caters to patients with such diseases.

What is Gene Therapy?

Gene therapy

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Understanding Chemical Reactions and Equilibrium in Systems

1. If there is a chemical reaction within a system, this system cannot be a closed system.

False – A closed system does not exchange matter with its surroundings. Mass is conserved in a chemical reaction. Therefore, it is possible that a reaction happens within a closed system as long as no mass is exchanged with its surroundings.

2. If there is a chemical reaction within a system, this system cannot be in equilibrium.

False – It is possible for a system to be in equilibrium even if a chemical

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Molecular Probes: Types and DNA Library Screening Techniques

Molecular Probes: Definition, Types, and Library Screening

A probe is a single-stranded sequence of DNA, RNA, or a specific protein/antibody that is labeled with a detectable marker (radioactive, fluorescent, or chemical tag) and used in molecular biology to detect the presence of a specific, complementary target sequence in a complex mixture.

Types of Probes

Probes are generally classified by their chemical nature and intended target:
  • DNA Probes: These are single- or double-stranded DNA sequences used
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Cellular Energy and Enzyme Function: Biochemistry Fundamentals

Cellular Life and Open Systems

Living cells function as open systems, constantly exchanging matter and energy with their environment.

Key System Definitions

  • Open System: A system that continuously exchanges matter and energy with its surroundings, transforming and storing energy to perform biological activities.
  • Equilibrium System: A system where the values of certain predefined variables are maintained over time within a range of tolerance.
  • Dynamic Balance of Flows: The typical state of living organisms,
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Genetic Modification and Uses of Transgenic Animals

Understanding Transgenic Animals

Transgenic animals are animals with a modified genome. A foreign gene is inserted into the animal’s genome to alter its DNA. This method is performed to improve the genetic traits of the target animal.

Initially, the improvement of genetic traits was achieved through selective breeding methods. In this process, animals with desired genetic characteristics were mated to produce offspring with improved traits. Since this technique was time-consuming and expensive, it

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