Clinical Case Studies: Diagnosis and Laboratory Interpretation in Internal Medicine

Case 1: Drug-Induced Hemolytic Anemia

A 43-year-old patient complains of back pain, darkened urine, general weakness, and dizziness that occurred after treating a cold with aspirin and ampicillin. Objectively, the patient is pale with subicteric sclera. Heart Rate (HR) is 98 bpm. The liver is palpable +2 cm, and the spleen is palpable +3 cm (hepatosplenomegaly).

Complete Blood Count (CBC) and Biochemical Analysis

  • RBCs: 2.6 × 1012/l
  • Hb: 60 g/l
  • Color Index: 0.9 (N: 0.85–1)
  • WBCs: 9.4 × 109/l
  • Basophils:
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Clinical Protocols for Major Chronic Diseases in Kazakhstan

1. Arterial Hypertension (AH): Diagnosis and Management

Topics Covered: Epidemiology of arterial hypertension (AH), classification, risk stratification (SCORE scale assessment of cardiovascular risk), laboratory and instrumental diagnostics of AH, diagnostic criteria, differential diagnosis of elevated blood pressure, and management strategy based on the degree of hypertension, risk groups, and comorbidities.

AH Management Summary:

Arterial Hypertension (AH) is a widespread chronic disease and a major

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Understanding Blood Health, Medical Terms, and Wellness

Understanding Blood Health and Related Medical Terminology

Blood:
The red liquid that circulates in the arteries and veins of humans and other vertebrate animals, carrying oxygen to and carbon dioxide from the body’s tissues.
Blood Cell / Célula Sanguínea:
Any of the kinds of cells normally found circulating in the blood (e.g., red cells, white cells, platelets).
Blood Type / Tipo de Sangre:
Another term for blood group, determined by the presence or absence of specific antigens on the surface of red
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Common Diseases of the Mouth, Pharynx, and Larynx

Stomatitis

Definition

  • Inflammation of the oral mucosa, which may involve the cheeks, gums, tongue, lips, and roof or floor of the mouth.

Etiology

  • Infectious: viral (e.g., *HSV*), bacterial, fungal (e.g., *candidiasis*).
  • Non-infectious: aphthous ulcers, trauma, nutritional deficiencies (B12, iron, folate), autoimmune diseases (e.g., *lichen planus*).
  • Irritants: poor oral hygiene, smoking, alcohol, spicy foods, certain medications (e.g., chemotherapy).

Clinical Features

  • Painful oral ulcers or erythema.
  • Swelling,
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Vocabulary and Idioms from World War II Contexts

Vocabulary and Phrases Reference

Gobsmacked

So shocked that you cannot speak.

Chuckle

Laugh quietly.

Not by a long chalk

Not in any way.

Imagen: not by a long chalk

Whooping

A loud cry of excitement.

Tutting

Sound made to show you disapprove of something.

Imagen: tutting

Mutterings

To grumble and speak in low tones.

Imagen: mutterings

It rained cat and dogs

It rained heavily.

Whipped away

To bring or take something quickly.

Imagen: whipped away

Clutching my hand

Hold something tightly in fear, worry, or pain.

Strapping boy

Strong and healthy.

Imagen: strapping boy

Confide

To trust.

Imagen: confide

His pride and joy

Someone important

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Human Sensory Organs and Nervous System Health

The Senses of Hearing

Diagram illustrating the structure and function of the human ear for hearing

Health of Sensory Organs

Vision Disorders

  • Short-sightedness (Myopia): Distant objects appear out of focus because the eyeball is too long, causing images to focus *in front of* the retina. Concave lenses or surgery can correct this.
  • Long-sightedness (Hypermetropia): Close objects appear out of focus because the eyeball is too short. This causes images to focus *behind* the retina. Convex lenses or surgery can correct this.
  • Astigmatism: Objects appear distorted or blurred. It is
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