Common Pediatric Surgical Conditions
Acute Hematogenous Osteomyelitis (AHO)
Pathophysiology
Bacteremia leads to bacteria localizing in the venous sinuses of long bones due to turbulent blood flow. This increases the risk of clotting and subsequent infection within the bone.
Progression of Infection Inside the Bone
- Phlegmon (inflammatory exudate) formation in the bone marrow
- Subperiosteal spread of the phlegmon (within 2-3 days)
- Spread to the nearest joint
- Spread of the phlegmon to soft tissue
- Sequestrum formation (dead bone tissue)
Septic Arthritis
AHO
Read MoreNervous Tissue: Structure, Function, and Types
Nervous Tissue: Structure, Function, and Types
Nervous tissue is a specialized tissue responsible for communication within the body. It originates from the ectoderm and consists of two main cell types: neurons and glial cells.
Functions of Nervous Tissue
- Detection and Transmission of Nerve Impulses: Neurons receive stimuli through receptors and transmit these impulses to the central nervous system (CNS). They also carry responses back to effector organs.
- Support and Protection: Glial cells provide structural
Genetics and Biotechnology: A Comprehensive Guide
Genetics and Biotechnology
Genome
The genome is the set of genes from one species. Genes are arranged on the chromosome that corresponds to it and the height of the chromosome that corresponds also (map of genes).
Gamete
A gamete is a reproductive cell that has the number of chromosomes halved. Humans have 46 chromosomes. Eggs and sperm are gametes with 23 chromosomes each.
Centromere
The centromere is the point on a chromosome where the two chromatids are joined. When a cell divides, the chromosome divides
Read MoreImmune System: Mechanisms of Specific Immune Response
Mechanisms of Specific Immune Response
Types of Leukocytes
- Basophils: Involved in allergic reactions, release heparin in tissues
- Lymphocytes: Responsible for specific immune response
- Monocytes: Phagocytose bacteria, dead cells, and organic matter; become macrophages in tissues
Types of Specific Immunity
- Antibody-Mediated Immunity (Humoral Response): Involves the production of antibodies by B lymphocytes
- Cell-Mediated Immunity (Cellular Response): Involves the activity of T lymphocytes and macrophages
Lymphocytes
Read MoreSymbiosis, Infection, and Immunity: A Comprehensive Guide
Symbiosis: Types and Examples
Symbiosis refers to the close and long-term interaction between two different species. There are four main types of symbiosis:
- Mutualism: Both species benefit from the interaction. Example: Bacteria in the human colon provide nutrients to the host, while the host provides a protective environment for the bacteria.
- Commensalism: One species benefits without significantly affecting the other. Example: Microscopic animals called hair follicle mites live on human skin without
Introduction to Human Biology and Health
Endocrine Glands
Endocrine glands are specialized cells of the secretory type, synthesizing chemicals called hormones.
Hormones
Hormones are chemical messengers that have these characteristics:
- They perform their function at a distance from where they are synthesized.
- They act in very small quantities.
Nervous System
Voluntary Act
A voluntary act is a deliberate and conscious response. The preparation of the response takes place in the brain.
Reflex
A reflex is an involuntary response. The nerve center involved
Read More