Understanding Wound Healing: A Cellular and Molecular Perspective
Wound Healing
Clotting, Scarring, and Re-establishment of Function in Complex Tissues
Four Stages of Wound Healing
HOMEOSTASIS (within minutes)
Stops the loss of blood and sets the stage for repair.
- Spilled blood and the fibrous clot
- Blood vessels become sticky.
- Sticky platelets flow to the area of the wound due to blood vessel damage.
- Platelet: Stem cell population, a piece of a megakaryocyte filled with vesicles for secreting growth factors (regulated secretion: makes a vesicle, but it sits there waiting
- Spilled blood and the fibrous clot
A Comprehensive Guide to Tongue Disorders: Symptoms, Causes, and Treatments
Classification of Tongue Disorders
Major Inherited, Congenital & Developmental Abnormalities
- Cleft, Lobed, Bifurcated, Tetrafurcated
- Aglossia (Hypoglossia)
- Macroglossia
Disorders of the Lingual Mucosa
- Changes in the Tongue Papilla
- Nonkeratotic and Keratotic White Lesions
- Depapilation and Atrophic Lesions
- Tertiary Syphilis and Interstitial Glossitis
- Pigmentation
Diseases Affecting the Body of the Tongue
- Infections
- Amyloidosis
- Neuromuscular Disorders
- Obstructive Sleep Apnea and Disorders
- TMJ Myofunctional Dysfunction
Malignant
Read MoreA Comprehensive Guide to Tongue Disorders: Symptoms, Causes, and Treatments
Classification of Tongue Disorders
Major Inherited, Congenital & Developmental Abnormalities
- Cleft, Lobed, Bifurcated, Tetrafurcated
- Aglossia (Hypoglossia)
- Macroglossia
Disorders of the Lingual Mucosa
- Changes in the Tongue Papilla
- Nonkeratotic and Keratotic White Lesions
- Depapilation and Atrophic Lesions
- Tertiary Syphilis and Interstitial Glossitis
- Pigmentation
Diseases Affecting the Body of the Tongue
- Infections
- Amyloidosis
- Neuromuscular Disorders
- Obstructive Sleep Apnea and Disorders
- TMJ Myofunctional Dysfunction
Malignant
Read MoreComprehensive Guide to Evolution and Biological Classification
Biological Classification and Evolution
Terms
Phylogeny: Evolutionary history and relationships (e.g., domains)
Phylogenetic Tree/Cladogram: Diagram reconstructing history based on morphology/physical behavior
Heterotrophic: Consumers (cannot produce their own food)
Autotrophic: Producers (can produce their own food – e.g., photosynthesis in plants)
Cephalization: Cluster/concentration of sensory organs (e.g., brain, nerves)
Binomial Nomenclature
Developed by Carl Linnaeus, binomial nomenclature uses genus
Read MoreEvolution and Classification of Life
Terms
Phylogeny: Evolutionary history and relationships (e.g., domains)
Phylogenetic Tree/Cladogram: Diagram reconstructing history based on morphology/physical behavior
Heterotrophic: Consumers (cannot produce their own food)
Autotrophic: Producers (can produce their own food – e.g., photosynthesis in plants)
Cephalization: Cluster/concentration of sensory organs (e.g., brain, nerves)
Carl Linnaeus
Binomial nomenclature: Uses genus and species names to name the organism (e.g., Homo sapiens, Escherichia
Viral Structure and Replication
1. Viral Structure
Hepadnaviruses
Enveloped
Virus Particle: Contains ds/ssDNA, unusual
Covering-Capsid: Protein coat surrounded by capsomers.
Envelope: (Not found in all viruses).
Central Core – Nucleic Acid Molecules: (DNA or RNA) Double/single strand DNA/RNA, every viron has it.
Matrix Proteins: Enzymes not found in all viruses.
HepB
- Break in skin/blood, STD
- Flu-like symptoms, jaundice
2 Shapes
- Helical
- Icosahedral
Non-Enveloped Viruses
Adenoviruses/Papillomaviruses/Polyomaviruses/Parvoviruses
Adeno
- Infect lymphoid
