Metabolic Processes: Krebs Cycle, Glycogen Storage & More

Posted on Aug 26, 2024 in Biology

1. Krebs Cycle

The Krebs cycle produces 1-12 moles of ATP.

2. Oxidative Decarboxylation

This is a multi-stage process involving NAD+, FAD, and lipoic acid.

3. Key Molecules

• Succinyl CoA
• NADH+, H+
• Oxaloacetate, acetyl-CoA, and water
• Citric acid

4. Location

The Krebs cycle occurs in the mitochondrial matrix and the inner membrane of the mitochondria.

5. Acetyl-CoA

The remaining Acetyl-CoA is continuously incorporated into the cycle.

6. NAD+

NAD+ plays a crucial role in the process.

7. Krebs Cycle and Glutamic Acid

The Krebs cycle is involved in the oxidative deamination of glutamic acid.

8. Malic Acid Oxidation

Oxidation of malic acid is a key step.

9. NADH Dehydrogenase

This enzyme is essential for the electron transport chain.

10. Proton Movement

Protons cross through a proton channel to the matrix.

11. ATP Synthase Activity

ATP synthase is responsible for ATP production.

12. UDP Glucose and Glycogen Phosphorylase

These molecules are involved in glycogen metabolism.

13. ATP Consumption/Production

No ATP is directly consumed or produced in this specific process.

14. Galactosemia

Galactosemia is caused by aldose reductase deficiency.

15. Glycogen Storage Disease Type II (Pompe Disease)

True or False:

16. Aldolase B Deficiency

Absence of aldolase B can lead to metabolic issues.

17. Renal Threshold for Glucose

This threshold is exceeded under certain conditions, such as during pregnancy in the neonate.

18. Sarcoplasmic Calcium Levels

An increase in sarcoplasmic calcium levels can affect muscle function.

19. Glucose 6-Phosphate Dehydrogenase Deficiency

This deficiency can lead to hemolytic anemia.

20. Lactase

Lactase is an enzyme responsible for lactose digestion.

21. McArdle Syndrome

True or False: