Understanding Muscle Contraction and Nervous System Functions
CHAPTER 9
What is the role of calcium ions in the contraction of skeletal muscle?
Calcium ions bind to the troponin-tropomyosin
The functional unit of a skeletal muscle fiber is the ______.
Sarcomere
Interactions between thin and thick myofilaments of the sacromere are responsible for ________.
Muscle contraction
During muscle contraction, all of the following occur EXCEPT ______.
Calcium concentrations in the sarcoplasm decrease
During a muscle contraction, muscle fibers shorten when ______.
Thin myofilaments are pulled toward the center of the sarcomere by the pivoting of the myosin heads
The elaborate network of membranes in skeletal muscle cells that functions in calcium storage is the ______.
Sarcoplasmic reticulum
What is the function of T tubules?
They conduct action potentials from the sarcolemma to the interior of the muscle cell
One transverse tubule plus two adjacent terminal cisternae form a _____.
Triad
Which links excitation to contraction in a skeletal muscle fiber?
Calcium
As action potentials travel down a T tubule, a voltage-sensitive protein changes shape. This shape change opens a ________.
Calcium release channel
The portion of the sarcolemma in contact with the axon terminals is called the _____.
Motor end plate
At the neuromuscular junction, calcium ions act to _______.
Release synaptic vesicles from the axon terminal
The first thing that occurs when the axon terminal releases ACh is ________.
Diffusion of ACh across the synaptic cleft
What type of ion channel opens in response to an action potential arriving at the axon terminal?
Voltage- gated calcium
What is the name of the enzyme that degrades ACh?
Acetylcholinesterase
Of the following muscle types, which is the only one subject to conscious control?
Skeletal
Which of the following muscular functions serves a metabolic function?
Heat generation
In order to receive a signal to contract, each skeletal muscle must be served by a(n) ______.
Nerve
Which of the following components accounts for the bulk of muscle fiber volume (up to 80%)?
Myofibrils
The thin filaments are not comprised of which of the following components?
Titin
What is the significance of the muscle fiber triad relationship?
The tubules conduct electrical impulses that stimulate calcium release from the sarcoplasmic reticulum
During a muscle contraction, the sliding filament theory would be apparent in a sarcomere because ______.
The H zone becomes less obvious and the Z discs move closer together
At the neuromuscular junction, the muscle contraction initiation event is ______.
Binding of acetylcholine to membrane receptors on the sarcolemma
In a muscle fiber, the key intracellular event that stimulates muscle contraction is known as ______.
Depolarization
During depolarization, the sarcolemma is most permeable to _____.
Sodium ions
What is calcium’s function during muscle contraction?
Calcium binds to troponin, changing its shape and removing the blocking action of tropomyosin
Small precise movements are controlled by _____ motor units
Small
A sprinter is likely to depend on ______ respiration to generate ATP, and a Tour de France cyclist is likely to rely on _____ respiration.
Anaerobic; aerobic
Sprinters typically possess more ______ muscle fibers.
Fast oxidative
A major difference between smooth muscle fibers and skeletal muscle fibers in terms of calcium influx is that _____.
Calcium ion influx occurs mostly from the extracellular fluid in smooth muscle
A major cellular feature in smooth muscle that contributes to its rhythmicity and ability to participate in peristalsis is the presence of _____.
Gap junctions
The principal neurotransmitter of skeletal muscle is acetylcholine. The major neurotransmitter of smooth muscle is ______.
Acetylcholine, epinephrine, norepinephrine
Electrical coupling by gap junctions is present in ______.
Unitary smooth muscle
CHAPTER 10
The muscle that provides the major force producing a specific movement is a _____.
Prime mover
You could conclude that a muscle with the term “rectus” included in its name is a muscle whose fibers run ____ to the body’s vertical axis
Parallel
Flexing the forearm with the biceps brachii is an example of which class of lever system?
Third class
When you bite down, this muscle strongly contract.
Masseter
When you lie on your back, your ______ muscles contract to lift your head.
Sternocleidomastoid
The muscles of the ______ are rather unusual for muscles because they insert onto the skin or other muscles.
Face
The _____ is/are the most important muscle for inspiratory breathing
Diaphragm
The levator ani and _____ muscles form the pelvic diaphragm.
Coccygeus
The ______ muscles include the supraspinatus, infraspinatus, teres minor, and subscapularis
Rotator cuff
Swimmers tend to have particularly well-developed ______ muscles.
Latissimus dorsi
The ____ muscle is the most powerful muscle in the body.
Quadriceps femoris
The _____ muscle comprise the triceps surae that inserts onto the calcaneal tendon and are prime movers of plantar flexion.
Gastrocnemius and soleus
CHAPTER 11
Information gathered by sensory receptors about internal and external changes
Processing and interpretation of sensory input
Activation of effector organs which produces a response
What are the effector organs?
muscles and glands
What is comprised of the brain and spinal cord, and is the integration and control center?
central nervous system
What system interprets sensory input and dictates motor output
central nervous system
What portion of the nervous system consists mainly of nerves?
peripheral nervous system
What types of nerves make up the PNS?
spinal and cranial
How many pairs of spinal nerves are in the PNS?
31
How many cranial nerves are in the PNS?
12
What are the function divisions of the PNS?
sensory and motor
Which division of the PNS is afferent?
sensory
Which division of the PNS is efferent?
motor
Which fibers in the PNS sensory (afferent) division convey impulses from skin, skeletal muscles, and joints to the CNS?
somatic sensory fibers
What fibers in the PNS sensory (afferent) division convey impulses from visceral organs to CNS?
visceral sensory fibers
What division of the PNS receives and sends towards the CNS?
afferent
Which division of the PNS moves from the CNS to muscles or glands?
efferent
Which division of the PNS transmit impulses from the CNS to muscles and glands?
efferent/motor
What are the divisions of the motor (efferent) division of the PNS?
somatic nervous system and autonomic nervous system
Which motor division of the PNS conducts impulses from CNS to skeletal muscles?
somatic nervous system
Which motor division of the PNS has visceral motor nerve fibers and regulates smooth muscle, cardiac muscle, and glands?
autonomic nervous system
What are the functional subdivisions of the autonomic nervous system?
sympathetic and parasympathetic
What is the fight or flight subdivision of the autonomic nervous system?
sympathetic
What is the rest and repose division of the autonomic nervous system?
parasympathetic
What are the main cell types in nervous tissue?
neuroglia and neurons (nerve cells)
What are the small cells in nervous tissue that surround and wrap delicate neurons?
neuroglia
What are excitable cells in nervous tissue that transmit electrical signals
neurons (nerve cells)
Which neuroglia pulls capillaries into the neuron to feed it, providing nutrition and oxygen, and gets rid of waste?
astrocytes
Which neuroglia protects the neuron – can transform to phagocytize micoorganisms and debris?
microglial cells
Which neuroglia range in shape from columnar to squamous, may be ciliated, and synthesize cerebrospinal fluid?
ependymal cells
Which neuroglia are branched cells that mylenate axons – wraps the axon with a myelin sheath?
oligodendrocytes
Which cells found in the PNS function similar to astrocytes by surrounding neuron cell bodies?
satellite cells
Which cells in the PNS are similar to oligodendrocytes by surrounding the nerve fibers and forming myelin sheaths?
Schwann cells
What helps improve and increase the speed of the electrical impulse along the axon?
myelin sheaths
What are the structural units of the nervous system; large specialized cells that conduct impulses?
neurons
What part of the neuron is the center – synthesizes proteins, membranes and other chemicals – integrates and interprets messages?
Neuron cell body (Perikaryon or Soma)
What are clusters of neuron cell bodies in the CNS?
nuclei
What lie along nerves in the PNS?
ganglia
What are armlike processes that extend from the neuron cell body?
neuron processes
What are bundles of neuron processes (axons) in the CNS?
tracts
What are bundles of neuron processes (axons) in PNS?
nerves
What are the types of neuron processes?
dendrites and axons
What neuron process in motor neurons collects information, and is the receptive region of the neuron?
dendrites
One axon per cell arises from the what?
axon hillock
What are the distal endings of the axon called?
axon terminals
What is the neuron cell membrane?
axolemma
What type of movement along the axon travels away from the cell body? (such as mitochondria, enzymes, membrane components)
anterograde
What type of movement along the axon goes toward the cell body? (such as viruses, signal molecules, bacterial toxins)
retrograde
What is the white-ish, protein-lipoid substance?
myelin
What are the functions of myelin?
protects and electrically insulates the axon, increases the speed of nerve impulse transmission
Myelination in the PNS is formed by what?
Schwann cells
What are the regions of the brain and spinal cord with dense collections of myelinated fibers?
white matter
What is mostly neuron cell bodies and nonmyelinated fibers
gray matter
What are the structural classifications of neurons?
multipolar, bipolar, unipolar
What are the functional classifications of neurons?
sensory, motor, interneurons
Which functional classification of neurons transmit impulses toward the CNS, and are almost all unipolar?
sensory
Which functional classification of neurons carry impulses from the CNS to muscles and glands, and are multipolar?
motor
Which functional classification of neurons shuttle signals through CNS pathways, lie between other neurons, comprise 99% of the body’s neurons and are most confined in the CNS?
interneurons
What is a measure of potential energy generated by a separated charge?
voltage
What is the flow of electrical charge (ions) between two points?
current
What is the hindrance to charge flow?
resistance
What is the substance with high electrical resistance?
insulator
What is the substance with low electrical resistance?
conductor
What are the types of ion channels?
leakage (non gated) and gated
Which type of channel is always open?
leakage (nongated)
What type of channel involves part of the protein
changing shape to open/close the channel?gated
67
Which type of gated channel open with binding of a specific neurotransmitter?
chemically gated
68
Which type of gated channel opens and closes in response to changes in membrane potential?
voltage gated
69
Which type of gated channel opens and closes in response to physical deformation of receptors (like sensory receptors)?
mechanically gated channels
70
What is the potential difference across the membrane of a resting cell?
resting membrane potential
71
Is the resting membrane polarized or depolarized?
polarized
72
The cell is ________ when more sodium is outside and more potassium is inside.
polarized
73
What is the decrease in membrane potential, wherein the inside of the membrane becomes less negative, and the probability of producing a nerve impulse increases?
depolarization
74
What is an increase in membrane potential, wherein the inside of the cell is more negative, and the probability of producing a nerve impulse is reduced?
hyperpolarization
75
For an axon to “fire” depolarization must reach what?
threshold
76
What is the voltage at which the action potential is triggered?
threshold
77
What is the fact that an AP either happens completely, or it doesn’t happen at all?
all or none phenomenon
ere!
