Medical Terminology: Root Words, Prefixes, Suffixes & More

Medical Terminology

Word Roots

Word RootMeaning
Abdomin/oAbdomen
Acr/oextremities
Aden/ogland
Adren/oadrenal gland
Adip/ofat
Aden/ogland
Adenoid/oadenoids
Albin/o, Leuk/owhite
Albumin/oalbumin
Aliment/onutrition
Alveol/oalveolus
Amni/oamniotic sac
Ankyl/obent, crooked, curved, stiff
Angi/o, Vas/o, Vascul/oblood vessel
Anis/ounequal
Aort/oaorta
Append/o, Appendic/oappendix
Aspir/oto breath in or suck in
Arthr/o, Articul/ojoint
Arteri/o, Arter/oArtery
Ather/oYellowish plaque or fatty material
Atri/oatrium
Audit/o, Audi/oHearing
Aur/o, Aur/i, Auricul/o, Ot/oEar
Bacteri/obacteria
Balan/oglans penis
Bil/o, Chol/obile
Blast/oimmature cell
Bronchi/o, Bronch/obronchus
Bucc/ocheek
Calc/ocalcium
Capn/o, Capn/Icarbon dioxide
Carcin/ocancer
Cardi/oheart
Carp/oCarpals
Caud/o, Infer/oDownward & toward the tail
Cerebr/obrain, cerebrum
Cerebell/ocerebellum
Cervic/ocervical neck, cervix
Cephal/oHead or upward
Cleid/o, Clavic/o, Clavicul/oClavicle
Chol/o, bil/obile
Chol/ebile, gall
Cheil/olip
Cholecyst/ogallbladder
Col/o, colon/ocolon
Colp/o, Vagin/ovagina
Cost/orib
colo, coloncolon (section of large intestine)
Conjunctiv/oConjunctiva
Corne/o, Kerat/oCornea
Coron/ocrown, encircle
crani/ocranium, skull
crin/osecrete
cry/ocold
Crypt/ohidden
cyan/oblue
Cyt/ocell
Cyst/o, Vesic/ourinary bladder
Dacryaden/oTear gland
Dent/o, ordont/otooth
derm/o, dermat/o, cutane/oskin
Diaphragmat/o, Phren/oDiaphragm
Dipl/odouble
Dips/othirst
Dist/oAway from or away from the point of attachment
Dors/oThe back
Duoden/oduodenum
Duct/olead, carry
Dur/odura mater
electr/oelectric, electricity
Enter/osmall intestine
erythr/ored
enchephal/oBrain
Epididym/oepididymis
Episi/o, Vulv/oExternal female genitalia
Esophag/oesophagus
Extendstraighten out
Evertturn outward
Femor/ofemur
fibr/ofiber
Fibul/ofibula
Flexbending
Gastr/ostomach
gli/oglue, glia cells
Glyc(os)/o, Gluc(os)/osugar, sweet
Gloss/o, Lingu/otongue
Glomerul/oglomerulus
Gravid/opregnancy
Gynec/o, Gyn/owoman
hem/o, hemat/oblood
Hepat/oliver
Herni/ohernia
hist/otissue
hydr/owater, watery fluid
hidr/osweat
Humer/ohumerus
Hypophys/opituitary gland
Hyster/o, Metri/o, Uter/oUterus
Invertturn inward
Ile/oileum
Ili/oIlium
Immun/oprotection, immunity
Ischi/oischium, hold back
Irid/o, Ir/oIris
Jejun/ojejunum
kerat/ohard, cornea
Ket/oketone
Labyrinth/oInner ear
Lacrim/o, Dacry/oTears
Lact/omilk
Laryng/olarynx
Later/otoward the side
Laryng/olarynx
Lei/o, leiomy/osmooth (muscle)
Leuk/owhite
Lip/ofat
Ligament/oLigament
Lingu/o, Gloss/otongue
Lob/olobe
Lumba/oLower back or side between ribs & pelvis
Lymph/olymph, lymphatic system
Lymphaden/olymph gland, lymph node
Medi/otoward the middle
Metacarp/ometacarpals
Metatars/ometatarsals
Metri/o, Uter/o, Hyster/oUterus
Melan/oblack, dark
Morph/oform, shape
Myx/omucus
My/o, Myos/omuscle
Myocardi/oCardiac muscle
Myc/ofungus
Myel/obone marrow and spinal cord
Narc/osleep
Nat/obirth
nephr/o, ren/okidney
necr/odeath of tissue
nucle/onucleus
neur/onerve
Nyctal/onight
onych/onail
Olig/ofew, scanty
Ophthalm/o, Opt/o, Ocul/oEye
Orch/o, Orchi/o, Test/o, Testicul/oTesticles, testes
Orchid/oTesticles, testes
Ordont/otooth
Orth/ostraight
Or/o, stomat/omouth
oste/obone
Ot/oear
Ovari/o, Oophor/oOvaries
Ov/o, Ov/I, Ovul/o, O/oOvum or Egg
Ox/o, Ox/aoxygen
Path/odisease
Pachy/othick
Palpebr/oEye lid
Patell/opatella
Pancreat/opancreas
Pelv/oPelvis
Pen/I, Phall/openis
Phalang/ophalanges
Phak/olens
Pharyng/opharynx
Phren/oDiaphragm
Pleur/opleura
Poster/o, Dors/oBack or behind
Pneumon/o, Pneum/o, Pulmon/oLung
Pneum/o, Pneumon/oAir
pulmon/olung
Pupill/o, Core/o, Cor/opupil
Pub/opubis
Proct/orectum, anus
Prostat/oprostate
Proxim/oNear or nearer to the point of attachment
Py/opus
Pylor/opylorus
Pyel/orenal pelvis
Sacr/oSacrum
Salping/ofallopian (uterine) tube
sarc/oflesh
Scapul/oscapula
Scler/osclera
Seb/osebum
Sialoaden/osalivary glands
Sigmoid/osigmoid colon
SomaBody
Somn/o(i)sleep
Spermat/o, Sperm/osperm
Spin/oSpine
Splen/ospleen
Spir/obreathing
Stern/osternum
Stomat/o, Or/omouth
Synovi/osynovial
Radi/oradius
Rhabdomy/oSkeletal muscle
Ren/o, nephr/okidney
Retin/oRetina
Rhin/o, Nas/onose
Rhytid/owrinkle
Tars/otarsal
Tendon/o, Tendin/o, Ten/otendon
Test/o, Testicul/o, Orch/o, Orchi/o, Orchid/oTesticles, testes
Thorac/oChest
Thromb/oclot
Thym/othymus
Thyr/o, Thyroid/othyroid gland
Tibi/otibia
Tonsill/otonsil
Toxic/opoison, poisoning
Trache/otrachea
Troph/onourishment
Trich/ohair
Tympan/o, Myring/oEar drum
Uln/oulna
Umbilic/onaval
Ureter/oureter
Urethr/ourethra
Ur/o, Urin/ourine or urinary system/tract
Uter/o, Metri/o, Hyster/outerus
Vagin/o, Colp/ovagina
Varix/coEnlarged vein
vasvessel
Valvul/ovalve
Ven/o, Phleb/ovein
Ventricul/oventricle
Ventr/o, Anteri/oThe front/belly side
Vertebr/o, spondyl/overtebra
Vesic/o, cyst/ourinary bladder
Viscer/ointernal organs
Vulv/o, Episi/oExternal female genitalia
Xanth/oyellow
Xer/odry

Prefixes

PrefixMeaning
A-, an-without, not, lack of
Ab-away from
Add-toward
Andro-masculine, male
Auto-self, same
Basi-, Baso-base
Bio-life
Brady-abnormally slow
Circum-around
Choroido-choroid
Crypt-hidden
Dia-through, complete
Dys-painful, difficult, abnormal
Dis-separate
Hemi-half
Hyper-Over, above normal, excessive
Hypo-Under, below normal, deficient
In-not
Em-in
Endo-inside, within
Epi-Above
Eso-inward
Eu-Good, normal, true
Ex-out
Exo-outward
Inter-between, among
Intra-inside, within
Macro-large, long
Micro-small
Mono-one
Nulli-none
Pan-all
Para-beside, other than
Per-through
Peri-around, surrounding
Poly-many, much, excessive
Post-after, behind
Pre-before
Primi-first
Pro-before, promoting
Pseudo-false
Quadri-four
Retro-backward, behind
Sub-, infra-below, beneath
Supra-, super-above
Syn-, Sym-joined together
Tachy-abnormally fast
Tetra-four
Trans-across, through
Ure-urine, urea

Suffixes

SuffixMeaning
-ac, -al, -ary, -ic, -ous, -tic, -arpertaining to
-algia, -dyniapain or ache
-aseenzyme
-astheniaweakness
-carcinomamalignant tumor of epithelial tissue
-celeherniation, protrusion
-cidesubstance that kills
-centesispuncture to aspirate
-crinesecretion
-cusishearing
-cytecell
-cytosistemporary increase in an abnormal condition
-dermaskin
-desissurgical binding or fusion
-dipsiothirst
-ectomyexcision, surgical removal
-ectasis, ectasiastretching, dilation
-edemaaccumulation of fluid in body tissues
-emiablood condition
-emesisvomiting
-genorigin, production
-genicoriginating, producing
-genesisformation & development
-gramrecord, recording
-graphinstrument used to record
-graphyprocess of recording
-gravidapregnant
-iasispresence or formation of
-ism, -iacondition of
-icle, -ole, -ulesmall
-itisinflammation
-iumpertaining to body region, structure
-ionprocess of
-ismthe state of
-istOne who specializes
-kinesiamovement
-lithstone, calculus
-logystudy of
-lysisbreakdown, destruction
-malaciasoftening
-megalyenlargement
-meterinstrument used for measuring
-metrymeasurement of
-osisabnormal condition
-omatumor
-opia, -opsiavision, sight
-optosisdrooping
-orrhaphysurgical suturing of
-orrhagiaexcessive flowing (blood), hemorrhage
-oxiaoxygen
-partum, -tocialabor, childbirth
-paresisweakness, slight paralysis
-pathyany disease
-peniadeficiency, decrease
-pepsiadigestion
-pexysurgical fixation
-phasiaspeech, speak
-phagiaeating
-phoniacondition of the voice
-plasiaproper formation, growth
-plastysurgical repair, reconstruction
-plegiaparalysis
-pneabreathing
-poiesisproduction, formation of
-ptysiscoughing or spitting
-ologistspecialist in
-rrheaflowing, discharge
-rrhexisrupture
-sarcomamalignant tumor of connective tissue
-sisaction, process, condition, or state
-scopelighted instrument used to view or examine
-scopyprocess of viewing or examining with lighted instrument
-spasminvoluntary movement
-stasisstopping, standing still
-stenosisnarrowing
-stomyartificial or surgical opening
-taxiacoordination
-tomyincision, cutting
-tocia, partumlabor, childbirth
-thoraxin the chest cavity
-toxinpoison
-tripsycrushing
-trophydevelopment, nutrition
-tropic, -tropinstimulating the function of
-tomecutting instrument
-umstructure
-uriaurination, urine

Singular and Plural Endings

Singular EndingRulePlural EndingExample
akeep -a, add -eaaevertebra (a spinal bone) -> vertebrae
endrop -en, add -inainaforamen (hole) -> foramina
exdrop -ex, add -icesicespollex (thumb) -> polices
iondrop -ion, add -iaiaganglion (nerve cell bodies) -> ganglia
isdrop -is, add -esesankylosis (stiff joint) -> ankyloses
isdrop -is, add -esestestis (male reproductive gland) -> testes
ondrop -on, add -aaspermatozoon (male sex cell) -> spermatozoa
ixdrop -ix, add -icesicesappendix -> appendices
iumdrop -ium, add -iaiaepithelium (tissue type) -> epithelia
umdrop -um, add -aaatrium (upper heart chamber) -> atria
usdrop -us, add -iinucleus (structure within a cell) -> nuclei
xdrop -x, add -gesgesphalanx (finger bone) -> phalanges
ydrop -y, add -iesiesbiopsy (tissue sample) -> biopsies

Terms for the Integument or Disease of the Integument

Arrector pili muscles: Tiny muscles that attach to the hair follicle

Keratin: Protein found in the hair and nails that promotes hardness

Melanin: Dark pigment produced in cells of the skin called melanocytes

Acne: Inflammatory disease of the sebaceous glands and hair follicles marked by pimples and pustules

Eczema: Inflammatory condition of the skin caused by irritants, food or chemicals

Impetigo: Acute, contagious skin disease caused by Streptococcus or Staphylococcus bacteria

Psoriasis: Chronic skin disease resulting in red patches with white/silver scales

Carcinoma: Malignant tumor of new growth derived from epithelial tissue

Terms for the Skeletal system or Diseases of the Skeletal System

Diaphysis: Shaft of long bones

Epiphysis: Ends of long bones

Epiphyseal plate: The growth area of a long bone

Periosteum: Fibrous membrane surrounding a bone

Endosteum: Membrane lining the central medullary cavity

Medullary: Cavity within a long bone’s shaft filled with bone marrow

Kyphosis: abnormal forward curvature; humpback

Lordosis: abnormal backward curvature

Scoliosis: abnormal lateral curvature

Terms for Joints or Diseases of Joints

Articulation: the site where bones come together; joint

Synovial joint: a joint that moves freely and contains synovial fluid in its cavity

Synovial fluid: Lubricating fluid in a freely movable joint

Ligament: band of strong connective tissue that connects bones or cartilage at a joint

Osteoarthritis: Inflammation of the bones and joints due to were and tear of the articular cartilage and bone

Rheumatoid Arthritis: Inflammation of joints Synovial membranes due to autoimmune degeneration of the connective tissue and joint.

Terms for Muscles or Diseases of Muscles

Striation: a minute groove, scratch, or channel especially when one of a parallel series

3 Muscle types: Skeletal (voluntary & striated), Smooth (involuntary & non-striated), Cardiac (involuntary & striated)

Fascicle: Bundle of muscle fibers

Agonist: Skeletal muscle which creates movement by contraction

Antagonist: Skeletal muscle which opposes an agonist muscle and relaxes when agonist contracts

Myasthenia gravis (MG): Neuromuscular disorder causing weakness and fatigue of voluntary muscles.

Muscular Dystrophy (MD): Hereditary condition causing progressive degeneration of the skeletal muscles.

Terms for Nervous system and Disease of the Nervous system

Cerebellum: posterior portion of the brain that coordinates the voluntary muscles and maintains balance and muscle tone

Cerebrum: largest and uppermost portion of the brain; divided into right and left halves

Brainstem: connects the brain to the spinal cord; consists of the pons and medulla oblongata

Diencephalon: area deep within the brain that contains the thalamus and hypothalamus

Ganglion: group of nerve cell bodies located along the pathway of a nerve

Cauda equine: “Horse tail”, collection of spinal nerves which branch off from the end of the spinal cord and exit at various levels.

Conus medullaris: Tapered, lower end of the spinal cord.

Filum terminale: Delicate strand of meninges which extends from the conus medullaris down to the sacrum and coccyx.

Sulcus: Groove or furrow, usually located on the outer cortex of the cerebrum.

Gyrus: Ridge located between two fissures or sulci on the cortex of the cerebrum.

Cerebrospinal fluid: Fluid located in ventricles of the brain and produced by choroid plexus located in each ventricle.

Multiple Sclerosis (MS): Immunological based disease where the immune system destroys the myelin sheath of nerves.

Paraplegia: Injury of the spinal cord below cervical vertebrae, which results in paralysis of the lower Half of the body.

Quadraplegia: Injury of the spinal cord within the cervical vertebrae, which results in paralysis of the limbs and lower body functions.

Terms for Special senses and Disease of the Eye and Ear

Choroid: Posterior middle vascular layer

Cerumen: Ear wax of external acoustic meatus.

Auditory Ossicles:

  • Malleus
  • Incus
  • Stapes

Cochlea: Inner ear structure responsible for hearing.

Vestibule: Chamber of the inner ear.

Accommodation: ability of the eye to adjust focus on near objects

Myringotomy: lancing of the tympanic membrane

Otitis Media: Inflammation of the middle ear caused by allergies, infections or fluid build-up.

Myopia: Nearsightedness

Hyperopia: Farsightedness

Diplopia: Double vision

Terms for Endocrine system and Diseases of the Endocrine system

Acromegaly: Excessive production of growth hormone in adulthood causes thick bones in extremities.

Diabetes Mellitus: Type I – Autoimmune disease resulting in the destruction of insulin producing cells (β-cells) of the pancreas, Type II – Resistance to insulin

Anterior Pituitary Gland

Growth Hormone (GH): Targets bone and tissues to stimulate growth and protein synthesis

Posterior Pituitary Gland

Antidiuretic Hormone (ADH): Targets kidneys to stimulate water reabsorption

Oxytocin (OXT): Stimulates uterine contractions (uterus) and milk ejection (breasts)

Thyroid Gland

Calcitonin: Maintains normal Ca2+ and PO43- levels in blood by reducing both

Thyroxine (T4): Regulates metabolism by increasing metabolic rate

Parathyroid Gland

Parathyroid Hormone (PTH): Maintains normal Ca2+ and PO43- levels in blood by increasing both

Adrenal Gland

Epinephrine: Responds to stress by increasing heart rate, blood pressure and expanding bronchial airways

Norepinephrine: Responds to stress by increasing blood pressure

Pancreas Gland

Glucagon: Stimulates storage of blood glucose to glycogen

Insulin: Stimulates blood glucose absorption by cells

Terms for Blood/lymphatic system and Diseases of the Blood/lymphatic system

Serum: Blood plasma without clotting elements

Granulocytes: White blood cells with visible granules within the cytoplasm, includes Basophil, Neutrophil & Eosinophil

Agranulocytes: White blood cells without visible granules within the cytoplasm, includes Lymphocyte & Monocyte

Organs of the Lymphatic System: Spleen, Thymus, Tonsils

Important lymph node locations in the body: Axillary (arm pits), Cervical (neck), Mediastinal (center of chest), Inguinal (groin).

Sickle Cell Anemia: Genetic blood disease due to a single amino acid change in the beta-hemoglobin protein, causing pain, fatigue and anemia

AIDS (Acquired Immunodeficiency Syndrome): Caused by HIV which target CD4+ T-helper cells where the virus replicates, ultimately destroying the cell.

Terms for Cardiovascular system and Diseases of the Cardiovascular system

Arteries: Vessels carrying blood away from the heart

Veins: Vessels carrying blood to the heart

Capillaries: Small blood vessels where gas and nutrient exchange with tissues occur

Atria: Upper receiving chambers of the heart

Ventricles: Lower pumping chambers of the heart

Valves: Structures located throughout the heart, arteries and veins which prevent the backflow of blood

Endocardium: Inner lining of the heart

Myocardium: Middle muscular layer of the heart tissue

Epicardium: Outer lining of the heart

Pericardium: Sac surrounding the heart which facilitates movement of the heart during contractions

Systole: Contraction phase, heart muscle pumps blood from chambers

Diastole: Relaxation phase, heart muscle relaxes & chambers fill w/blood

Sphygmomanometer: Device which measures blood pressure

Heart murmurs: Failure of heart valves to close firmly causing leaking of blood usually caused by stenosis of the heart valves

Heart attack: Death of cardiac muscle tissue usually due to coronary artery blockage

Cardiac arrest: Sudden loss of cardiac activity, usually due to irregular heart rhythms and electrical signals

Hypertension: Persistently high blood pressure

Terms for Respiratory system and Diseases of the Respiratory system

Pneumonia: bacterial infection of the lung causing inflammation and loss of lung function. Mainly due to the bacteria Streptococcus pneumoniae.

Chronic Obstructive Pulmonary Disease (COPD): Narrowing of the small bronchi, which hinders or slows expiratory flow. Can be permanent or temporary.

Conditions leading to COPD are:

  • Asthma
  • Bronchitis
  • Emphysema

Terms for Digestive system and Diseases of the Digestive system

Deglutition: Swallowing

Mastication: Chewing

Peristalsis: Wave-like movement of muscles that push substances along their length

Sphincters: Valves located along the length of the digestive tract which regulate food movement & prevents food moving backwards.

Jaundice: Yellow discoloration of the skin and eyes due to excess bilirubin in the blood.

Crohn’s Disease: Chronic inflammation of the intestines causing ulcers and thickening of the intestinal walls.

Terms for Urinary system and Diseases of the Urinary system

Micturition: Process of expelling or voiding urine

Hydronephrosis: “water inside the kidney” – Obstruction of urine flow out of the kidney usually due to kidney stones.

Hydroureter: “water inside the ureter” – Obstruction of urine flow out of the ureter usually due to kidney stones.

Kidney stones: Small hard mineral deposits with acid salts which form inside kidneys

  • Caused by dehydration, gout, excessive vitamin D, animal protein, sugar, & salt

Terms for Reproductive systems and Diseases of the Reproductive system

Genitalia: Male and Female reproductive organs

Hernia: Organ or tissue protrudes through muscle or connective tissue

Inguinal hernia: Intestine or bladder protrudes through the abdominal wall or inguinal canal (common in men)

Femoral hernia: Intestine or bladder protrudes through the canal carrying the femoral artery (common in women)

Ovulation: Release of the ovum from the ovary

Endometriosis-The transplant of functional endometrial tissue in locations other than the lining of
  the uterus
Breast Cancer-Tumor originating in the breast
~246,660 new cases of invasive breast cancer is estimated for 2016
~40,450 will die of breast cancer in 2016
~15% is genetic (BRCA1, BRCA2)