Medical Emergencies & Essential Drug Interventions

Medical Emergency Classification & Management

A medical emergency is an injury or illness that poses an immediate threat to a person’s life or long-term health, requiring prompt intervention.

System-Oriented Classification of Emergencies

This classification lists major organ systems and discusses life-threatening situations associated with those systems.

Broad Categories of Emergencies

  • Cardiovascular: Conditions affecting the heart and blood vessels.
  • Non-Cardiovascular: Emergencies not primarily involving the cardiovascular system.
  • Stress-Related: Conditions triggered or exacerbated by stress.
  • Non-Stress-Related: Emergencies occurring independently of stress.

Detailed System-Based Emergencies

  • Infectious Diseases
  • Immune System: Allergies, angioedema, contact dermatitis, anaphylaxis.
  • Skin and Appendages
  • Eyes, Ear, Nose, and Throat (ENT)
  • Respiratory Tract: Asthma, hyperventilation.
  • Cardiovascular System (CVS): Arteriosclerotic heart disease, angina pectoris, myocardial infarction (MI), heart failure.
  • Blood Disorders
  • Gastrointestinal Tract (GIT) / Liver Disorders
  • Obstetrics / Gynecology
  • Nervous System: Unconsciousness, vasovagal syncope, orthostatic hypotension.
  • Convulsive Disorders: Epilepsy.
  • Drug Overdose Reactions
  • Cerebrovascular Accident (Stroke)
  • Endocrine Disorders: Diabetes Mellitus (hypo- or hyperglycemia).
  • Thyroid Gland: (Hypo- or hyperthyroidism).
  • Adrenal Gland: Acute adrenal insufficiency.

Non-Cardiovascular Emergencies

Stress-Related Non-Cardiovascular Emergencies

  • Hyperventilation
  • Seizure
  • Acute Adrenal Insufficiency
  • Thyroid Storm
  • Asthma (Bronchospasm)

Non-Stress-Related Non-Cardiovascular Emergencies

  • Orthostatic Hypotension
  • Drug Overdose Reaction
  • Hypoglycemic Reaction
  • Hyperglycemia
  • Allergy

Cardiovascular Emergencies

Stress-Related Cardiovascular Emergencies

  • Angina Pectoris
  • Acute Heart Failure
  • Cerebral Ischemia or Infarction

Non-Stress-Related Cardiovascular Emergencies

  1. Acute Myocardial Infarction

Essential Emergency Medications

Understanding the critical drugs used in medical emergencies is vital for effective intervention.

Nitroglycerin

Drug Class/MechanismActions/PropertiesIndicationsAdverse Effects/Contraindications
Vasodilator
Increases release of nitric oxide
Rapid onset of action: 1-2 min
Shelf life of tablets: 12 weeks
  • Acute angina attack
  • Early management of Myocardial Infarction (MI)
  • Acute hypertensive episodes
Headache
Facial flushing
Hypotension

Salbutamol (Albuterol)

Drug Class/MechanismActions/PropertiesIndicationsAdverse Effects/Contraindications
Bronchodilator
Beta-2 agonist
Specific bronchial smooth muscle relaxant
1-2 inhalations every 4-6 hours
  • Acute asthma episodes
  • Allergic reactions causing bronchospasm
Tachycardia
Arrhythmias

Aspirin

Drug Class/MechanismActions/PropertiesIndicationsAdverse Effects/Contraindications
Antiplatelet
Irreversibly acetylates platelet cyclooxygenase
Inhibits production of thromboxane A2 (antithrombotic effect)
Rapid antiplatelet actionSuspected myocardial infarction or unstable angina pectorisHemorrhage (e.g., bleeding peptic ulcer)

Epinephrine (Adrenaline)

Drug Class/MechanismActions/PropertiesIndicationsAdverse Effects/Contraindications
Catecholamine
Agonist at both alpha and beta adrenergic receptors
Rapid onset of action
Potent bronchodilator (beta-2)
Physiological antagonist of histamine
Vasopressor (alpha)
Increases Heart Rate (HR), Cardiac Output (CO), Blood Pressure (BP)
  • Acute allergic reaction/anaphylaxis (1:1000 concentration)
  • Cardiac arrest (1:10,000 concentration)
Arrhythmias
Pregnant women: decreased placental blood flow

Chlorpheniramine

Drug Class/MechanismActions/PropertiesIndicationsAdverse Effects/Contraindications
Antihistaminic (H1 blocker)
Competitive antagonist at H1 receptors
Prevents the actions of histamine
  • Delayed-onset allergic reactions
  • Acute allergic reaction/anaphylaxis (adjunctive)
Sedation
Decreased blood pressure
Thickening of respiratory secretions
Avoid in asthmatics